From South Bay
Take I-5 North (toward Los Angeles)
Take I-8 East (toward El Centro)
Take Qualcomm Way Exit
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive
OR..
Take I-805 North
Take I-8 West
Take Qualcomm Way Exit
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive

From North County Coastal (including Los Angeles and Orange County)
Take I-5 South
Take I-8 East
Take Qualcomm Way Exit
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive

From North County Inland (including the Inland Empire)
Take I-15 South
Take Friars Road Exit (go right towards Qualcomm Stadium)
Turn left on River Run Drive
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive

From the Beaches
Take I-8 East
Take Qualcomm Way Exit
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive

From East County
Take 94 West
Take I-805 North
Take I-8 West
Take Qualcomm Way Exit.
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive
OR..
Take I-8 West
Take Qualcomm Way Exit
Turn Right on Rio San Diego Drive
Arrive at 8989 Rio San Diego Drive